In this work we consider a system of infinitely many interacting diffusions as a marked Gibbs point process. With this perspective, we show, for a large class of stable and regular interactions, existence and (conjecture) uniqueness of an infinite-volume Gibbs process. In order to prove existence we use the specific entropy as a tightness tool. For the uniqueness problem, we use cluster expansion to prove a Ruelle bound, and conjecture how this would lead to the uniqueness of the Gibbs process as solution of the Kirkwood-Salsburg equation.