Daniel Schindler
Mathematical modeling and simulation of protrusion-driven cell dynamics
PhD thesis, Uni Potsdam, October 2023
Supervision: Prof. Wilhelm Huisinga, Prof. Matthias Holschneider
Sabine Stübler
Mathematical model of the mucosal immune response to study inflammatory bowel diseases and their treatment
PhD thesis, Uni Potsdam, October 2023
Supervision: Prof. Wilhelm Huisinga
Kolja Wichmann
Konsistenz der Posterior-Verteilung in der bayesschen Statistik
Bachelor thesis, Uni Potsdam, October 2023
Supervision: Prof. Wilhelm Huisinga
Ruben Taieb
Model misspecification diagnosis in mixed effects models through SDEs
Master internship, ENS Lyon, April-July 2023
Supervision: Dr. Niklas Hartung
Aleksandra Khatova
Exploring vine copulas as surrogate models for multivariate distributions
Master thesis, Uni Potsdam, June 2023
Supervision: Dr. Niklas Hartung
Tom Rodenhagen
Stochastische Differentialgleichungen zur Behandlung von Missspezifkationen in der Pharmakokinetik
Master thesis, Uni Potsdam, Oct 2021
Supervision: Dr. Niklas Hartung
Carolin Kirchner
Optimal design in nonlinear dose-response models
Bachelor thesis, Uni Potsdam, Aug 2021
Supervision: Dr. Niklas Hartung, Dr. Kathrin Roth (Bayer AG)
Corinna Maier
Bayesian data assimilation and reinforcement learning for model-informed precision dosing in oncology
PhD thesis, Uni Potsdam, July 2021
Supervision: Prof. Wilhelm Huisinga
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Jane Knöchel
Model reduction of mechanism-based pharmacodynamic models and its link to classical drug effect models
PhD thesis, Uni Potsdam, December 2019
Supervision: Prof. Wilhelm Huisinga
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Adrian Geldner
Eine Einführung in die Maß- und Integrationstheorie aus Sicht der Stochastik
BSc thesis, Uni Potsdam, Juli 2019
Supervision: Prof. Wilhelm Huisinga, Peter Mahns
Saskia Fuhrmann
Physiologically-based pharmacokinetic and mechanism-based pharmacodynamic modelling of monoclonal antibodies with a focus on tumour targeting
PhD thesis, Uni Potsdam, October 2018
Supervision: Prof. Wilhelm Huisinga
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Florian Mikolajczak
Impact of Parameter Estimates Correlations in Optimal Design
Master thesis, Univ Potsdam, Feb 2018
Supervision: Dr. Niklas Hartung
Christoph Hethey
Cell physiology based pharmacodynamic modeling of antimicrobial drug combinations
PhD thesis, Uni Potsdam, September 2017
Supervision: Prof. Wilhelm Huisinga
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Noel Stein
Eine Methode der stochastischen Approximation
Bachelor thesis, Univ Potsdam, May 2017
Supervision: Prof. Wilhelm Huisinga, Dr. Niklas Hartung
Alexander Solms
Integrating nonlinear mixed effects and physiologically–based modeling approaches for the analysis of repeated measurement studies
PhD thesis, Uni Potsdam, May 2017
Supervision: Prof. Wilhelm Huisinga
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Arved Jeltsch
Physiologically-based Pharmacokinetic Model of Aluminium in Rats & Human
Master thesis, Univ Potsdam, May 2017
Supervision: Prof. Wilhelm Huisinga
Moritz Lell
Bayesian inference of viral fitness costs in the context of resistance accumulation during HIV therapy
Master thesis, Univ Potsdam, January 2017
Supervision: Jane Knöchel, Prof. Wilhelm Huisinga
Sathej Gopalakrishnan
Mathematical modelling of host-disease-drug interactions in HIV disease
PhD thesis, Uni Potsdam, March 2016
Supervision: Prof. Wilhelm Huisinga
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Tino Schönke
Koexistenz verteidigter und unverteidigter Phänotypen bei phänotypischer Plastizität in Räuber-Beute-Modellen
MSc thesis, Univ Potsdam, September 2015
Supervision: Dr Michael Sieber, Prof. Wilhelm Huisinga
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Ludivine Fronton
Modeling Approaches to Characterize the Disposition of Monoclonal Antibodies
PhD thesis, Univ Potsdam, November 2014
Supervision: Prof. Wilhelm Huisinga
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Florian Hildebrandt
Konvergenzanalyse der Quasi-Steady-State Approximation im Rahmen der Theorie singulär gestörter Differentialgleichungen
BSc thesis, Univ Potsdam, April 2014
Supervision: Prof. Wilhelm Huisinga, Prof. Carsten Hartmann (FU Berlin)
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Stephan Menz
Hybrid Stochastic-Deterministic Approaches for the Simulation and Analysis of Biochemical Reaction Networks
PhD thesis, FU Berlin, Decembre 2012
Supervision: Prof. Wilhelm Huisinga, Prof. Christof Schütte (FU Berlin)
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Fanny Wegner
A stochastic model of the cell movement of Dictyostelium discoideum in the absence of external cues
Master thesis, Institut für Biochemie und Biologie. Universität Potsdam, Dezember 2012
Supervision: Prof. Wilhelm Huisinga, Prof. Carsten Beta.
Sophie Schneider
Covariate modeling in population pharmacokinetics: comparing the classical covariate screening approach to a new physiologically-based approach exemplified for Tobramycin
Master thesis, Institut für Biochemie und Biologie. Universität Potsdam, Dezember 2012.
Supervision: Prof. Wilhelm Huisinga
Karsten Silow
Der thermodynamische Limes von Reaktionssystemen
Diploma thesis, Universitaet Potsdam, December 2011.
Supervision: Prof. Wilhelm Huisinga
Sabine Pilari
Novel Approaches to Mechanistic Pharmacokinetic/Pharmacodynamic Modeling
PhD thesis, FU Berlin, April 2011.
Supervision: Prof. Wilhelm Huisinga
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Ben-Fillippo Krippendorff
Integrating Cell-level Kinetic Modeling into the Optimization of Cancer Therapeutics
Ph.D. Thesis, National University of Ireland, Maynooth, Apr 2010.
Supervision: Prof. Wilhelm Huisinga
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Max von Kleist
Combining Pharmacology and Mutational Dynamics to Understand and Combat Drug Resistance in HIV
Ph.D. Thesis, National University of Ireland, Maynooth, Dec 2009.
Supervision: Prof. Wilhelm Huisinga
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Andrea Y. Weisse
Global Sensitivity Analysis of Ordinary Differential Equations
PhD thesis, FU Berlin, July 2009.
Supervision: Prof. Wilhelm Huisinga
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Stephan Menz
Understanding Differences between Stochastic and Deterministic Models of Chemical Reaction Networks
Master thesis, FU Berlin, August 2008.
Supervision: Prof. Wilhelm Huisinga
Sabine Pilari
Influence of the Dynamics of IKK Activation and Inactivation on the NFkB Signaling Pathway
Master thesis, FU Berlin, March 2008.
Supervision: Prof. Wilhelm Huisinga
Wai-Cheung Ng
Entwicklung eines PBPK-Modells zur Analyse der nichtlinearen Pharmakokinetik von Compound B
Bachelor thesis, FU Berlin, August 2006
Supervision: Prof. Wilhelm Huisinga, M. Schultze-Mosgau (Schering AG, Berlin)
Sabine Pilari
Entwicklung eines physiologie-basierten Pharmakokinetikmodells zur Untersuchung des Einflusses einer erhöhten Konzentration an Sexualhormonbindendem Globulin auf die Pharmakokinetiken von Compound A
Bachelor thesis, FU Berlin, August 2006
Supervision: Prof. Wilhelm Huisinga, C. Klein (Schering AG, Berlin).
Max von Kleist
A Generic Physiologically Based Pharmacokinetic Model to Predict Drug Distribution in Plasma, Red Blood Cells, Interstitial and Cellular Space with Application to the Pharmacokinetics of Tolbutamide
M.Sc. Thesis, Freie Univeristät Berlin, 2005.
Supervision: Prof. Wilhelm Huisinga
Sebastian Ueckert
Entwicklung eines PBPK-Modells zur Beschreibung der Akkumulation von Folaten in Erythrozyten
Bachelor thesis, FU Berlin, August 2006,
Supervision: Prof. Wilhelm Huisinga, S. Reif (Schering AG, Berlin).
Ben-Fillippo Krippendorff
In-silico Modellierung der Cytochrom-P450 Kinetik zur Analyse von CYP-Inhibitionsassays
Bachelor thesis, FU Berlin, September 2005,
Supervision: Prof. Wilhelm Huisinga, A. Reichel (Schering AG, Berlin).
Reiner Matthiesen
Mathematische Modellierung der Regulation der Flagellensynthese bei Escherichia coli
Diploma thesis, FU Berlin, September 2004,
Supervision: Prof. Wilhelm Huisinga, Prof. R. Hengge.
